Fragrance in the products we use can be harmful to your health and that of your unborn child.
There are two types of musk used in fragrances, personal care products, and cosmetics.
One is nitromusks, which include musk keytones and polycyclic musk which are Galaxolide and Tonalide.
One is nitromusks, which include musk keytones and polycyclic musk which are Galaxolide and Tonalide.
Synthetic musks (Galaxolide and Tonalide) are used in many personal care products, such as lotions, perfumes, colognes and body sprays.
There is evidence that exposure to synthetic musk have been shown that they can affect androgen and progesterone receptors.
There is evidence that exposure to synthetic musk have been shown that they can affect androgen and progesterone receptors.
Tonalide is also identified as a photo sensitizer – what does that mean for us?
It means it is releasing toxins into our bodies, and into the bodies of our unborn children. Synthetic musks have been found in the umbilical cord blood and 7 out of 10 babies have been born with Tonalide and/or Galaxolide already in their blood.
Synthetic musks have been found in the blood of young adults and also in mothers breast milk. So the next time you spray on that fragrance, or lather that body lotion on to soften your skin, you might want to think about what else it might be doing to you and your loved ones…
Further Information can be found in these articles:
i. Parker RD, Buehler EV, Newmann EA. 1986. Phototoxicity, photoallergy, and contact sensitization of nitro musk perfume raw materials. Contact Dermatitis. 14(2): 103-9.
ii. Environmental Working Group (EWG) 2009. Pollution in Minority Newborns. Available: http://www.ewg.org/minoritycordblood.
iii. Seinen W, Lemmen JG, Pieters RH, Verbruggen EM, Van der Burg B. (1999). AHTN and HHCB show weak estrogenic but no uterotrophic activity. Toxicol. Lett. 111, 161–168.
iv. Schreurs RH, Sonneveld E, Jansen JH, Seinen W, van der Burg B. 2005. Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays. Toxicol Sci. 83(2): 264-72.
v. Bitsch N, Dudas C, Körner W, Failing K, Biselli S, Rimkus G, Brunn H. 2002. Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells. Arch Environ Contam Toxicol. 43(3): 257-64.
vi. European Union Risk Assessment Report. 2008a.1-(5,6,7,8-TETRAHYDRO-3,5,5,6,8,8-HEXAMETHYL-2-NAPHTHYL)ETHAN-1-ONE (AHTN) CAS No: 1506-02-1 or 21145-77-7. Available: http://ecb.jrc.ec.europa.eu/home.php?CONTENU=/DOCUMENTS/Existing-Chemicals/
vii. Steinberg P, Fischer T, Arand M, Park E, Elmadfa I, Rimkus G, Brunn H, Dienes HP. (1999). Acute hepatotoxicity of the polycyclic musk 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphtaline (AHTN). Toxicol Lett.,111(1-2), pp151-60.
viii. Rimkus, G.G. and M. Wolf, Polycyclic musk fragrances in human adipose tissue and human milk. Chemosphere, 1996. 33(10): p. 2033-43.
ix. Hutter HP, Wallner P, Moshammer H, Hartl W, Sattelberger R, Lorbeer G, Kundi M. 2005. Blood concentrations of polycyclic musks in healthy young adults. Chemosphere. 59(4): 487-92.
x. Hutter, HP, P Wallner, H Moshammer,W Hartl , R Sattelberger, G Lorbeer and M Kundi. 2009. Synthetic musks in blood of healthy young adults: Relationship to cosmetics use. Science of the Total Environment 407:4821-4825.
xi. Lignell S, Darnerud PO, Aune M, Cnattingius S, Hajslova J, Setkova L, Glynn A. 2008. Temporal trends of synthetic musk compounds in mother’s milk and associations with personal use of perfumed products. Environ Sci Technol. 42(17): 6743-8.
xii. U.S. Environmental Protection Agency (USEPA). 2009a. Inventory Update Reporting (IUR) Data for 2006. Available: http://www.epa.gov/iur/
xiii.
Dietrich DRandHitzfeld BC . 2004. Bioaccumulation and Ecotoxicity of Synthetic Musks in the Aquatic Environment. In: The Handbook of Environmental Chemistry, volume 3, part X: 233-244 (Springer Berlin/Heidelberg).
xiv. Chen D, Zeng X, Sheng Y, Bi X, Gui H, Sheng G, Fu J. 2007. The concentrations and distribution of polycyclic musks in a typical cosmetic plant. Chemosphere. 66(2):252-8.
xv. Rüdel H, Böhmer W, Schröter-Kermani C. 2006. Retrospective monitoring of synthetic musk compounds in aquatic biota from German rivers and coastal areas. J Environ Monit. 8(8): 812-23.
xvi. Kannan K. Reineer JL, Yun SH. Perotta EE, Tao L, Johnson-Restrepo B, Rodan BD. 2005. Polycyclic musk compounds in higher trophic level aquatic organisms and humans from theUnited States . Chemosphere 61: 693–700.
ii. Environmental Working Group (EWG) 2009. Pollution in Minority Newborns. Available: http://www.ewg.org/minoritycordblood.
iii. Seinen W, Lemmen JG, Pieters RH, Verbruggen EM, Van der Burg B. (1999). AHTN and HHCB show weak estrogenic but no uterotrophic activity. Toxicol. Lett. 111, 161–168.
iv. Schreurs RH, Sonneveld E, Jansen JH, Seinen W, van der Burg B. 2005. Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays. Toxicol Sci. 83(2): 264-72.
v. Bitsch N, Dudas C, Körner W, Failing K, Biselli S, Rimkus G, Brunn H. 2002. Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells. Arch Environ Contam Toxicol. 43(3): 257-64.
vi. European Union Risk Assessment Report. 2008a.1-(5,6,7,8-TETRAHYDRO-3,5,5,6,8,8-HEXAMETHYL-2-NAPHTHYL)ETHAN-1-ONE (AHTN) CAS No: 1506-02-1 or 21145-77-7. Available: http://ecb.jrc.ec.europa.eu/home.php?CONTENU=/DOCUMENTS/Existing-Chemicals/
vii. Steinberg P, Fischer T, Arand M, Park E, Elmadfa I, Rimkus G, Brunn H, Dienes HP. (1999). Acute hepatotoxicity of the polycyclic musk 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphtaline (AHTN). Toxicol Lett.,111(1-2), pp151-60.
viii. Rimkus, G.G. and M. Wolf, Polycyclic musk fragrances in human adipose tissue and human milk. Chemosphere, 1996. 33(10): p. 2033-43.
ix. Hutter HP, Wallner P, Moshammer H, Hartl W, Sattelberger R, Lorbeer G, Kundi M. 2005. Blood concentrations of polycyclic musks in healthy young adults. Chemosphere. 59(4): 487-92.
x. Hutter, HP, P Wallner, H Moshammer,
xi. Lignell S, Darnerud PO, Aune M, Cnattingius S, Hajslova J, Setkova L, Glynn A. 2008. Temporal trends of synthetic musk compounds in mother’s milk and associations with personal use of perfumed products. Environ Sci Technol. 42(17): 6743-8.
xii. U.S. Environmental Protection Agency (USEPA). 2009a. Inventory Update Reporting (IUR) Data for 2006. Available: http://www.epa.gov/iur/
xiii.
Dietrich DRand
xiv. Chen D, Zeng X, Sheng Y, Bi X, Gui H, Sheng G, Fu J. 2007. The concentrations and distribution of polycyclic musks in a typical cosmetic plant. Chemosphere. 66(2):252-8.
xv. Rüdel H, Böhmer W, Schröter-Kermani C. 2006. Retrospective monitoring of synthetic musk compounds in aquatic biota from German rivers and coastal areas. J Environ Monit. 8(8): 812-23.
xvi. Kannan K. Reineer JL, Yun SH. Perotta EE, Tao L, Johnson-Restrepo B, Rodan BD. 2005. Polycyclic musk compounds in higher trophic level aquatic organisms and humans from the